Methylenetetrahydrofolate reductase gene polymorphisms and the prenatal risk of Down syndrome

Methylenetetrahydrofolate reductase gene polymorphisms and the prenatal risk of Down syndrome

The relationship between the metabolism of B9 vitamins (folates) and chromosomal nondisjunction leading to aneuploidy has drawn attention in the recent past. Here, we examine two polymorphisms in the gene encoding the folate metabolizing enzyme methylenetetrahydrofolate reductase and their impact up...

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Bibliographic Details
Main Authors: Ruxandra Cretu, Daniela Neagos, Andreea Tutulan-Cunita, Laurentiu Camil Bohiltea, Veronica Stoian
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2010-06-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/752

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