Agent-based dynamic knowledge representation of <it>Pseudomonas aeruginosa </it>virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis
<p>Abstract</p> <p>Background</p> <p>There is a growing realization that alterations in host-pathogen interactions (HPI) can generate disease phenotypes without pathogen invasion. The gut represents a prime region where such HPI can arise and manifest. Under normal cond...
Main Authors: | Zaborina Olga, Alverdy John C, Seal John B, An Gary |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2011-09-01
|
Series: | Theoretical Biology and Medical Modelling |
Online Access: | http://www.tbiomed.com/content/8/1/33 |
Similar Items
-
Pseudomonas aeruginosa overrides the virulence inducing effect of opioids when it senses an abundance of phosphate.
by: Alexander Zaborin, et al.
Published: (2012-01-01) -
Prevention of siderophore- mediated gut-derived sepsis due to <it>P. aeruginosa </it>can be achieved without iron provision by maintaining local phosphate abundance: role of pH
by: Gerdes Svetlana, et al.
Published: (2011-09-01) -
Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak.
by: Andrea D Olivas, et al.
Published: (2012-01-01) -
The evolution of virulence in the opportunistic pathogen Pseudomonas aeruginosa
by: Day, Alexander
Published: (2017) -
Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions
by: Ansel Hsiao, et al.
Published: (2020-01-01)