Cytogenetic characterization and <it>H-ras </it>associated transformation of immortalized human mammary epithelial cells

<p>Abstract</p> <p>Introduction</p> <p>Immortalization is a key step in malignant transformation, but immortalization alone is insufficient for transformation. Human mammary epithelial cell (HMEC) transformation is a complex process that requires additional genetic chan...

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Bibliographic Details
Main Authors: Larivee Siobhan, Wolfe Kristine, Bryant Eileen, Bonnet George, Opheim Kent E, Alper Özge, Rao Krishna, Porter Peggy, McDougall James K
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/6/1/15