Upregulated 5-HT1A receptor-mediated currents in the prefrontal cortex layer 5 neurons in the 15q11–13 duplication mouse model of autism

Upregulated 5-HT1A receptor-mediated currents in the prefrontal cortex layer 5 neurons in the 15q11–13 duplication mouse model of autism

Abstract Serotonin (5-HT) is a well-known modulator of behavioral, physiological, and emotional functions of the forebrain region. We recently discovered alterations of serotonergic synaptic modulations in both, the prefrontal cortex (PFC) and the somatosensory cortex, in the 15q dup mouse model of...

Full description

Bibliographic Details
Main Authors: Fumihito Saitow, Toru Takumi, Hidenori Suzuki
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Brain
Subjects:
5-HT1A receptor
Autism
Developmental disorder
Prefrontal cortex
Serotonin
Synapse
Online Access:http://link.springer.com/article/10.1186/s13041-020-00655-9

Internet

http://link.springer.com/article/10.1186/s13041-020-00655-9

Similar Items