2-Deoxyglucose Reverses the Promoting Effect of Insulin on Colorectal Cancer Cells In Vitro.

An increased risk of colorectal cancer is related to the development of metabolic syndromes including hyperglycemia, and hyperinsulinemia. The high circulatory levels of glucose and/or insulin or the application of exogenous insulin may promote carcinogenesis, cancer progression and metastasis, whic...

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Bibliographic Details
Main Authors: Dongsheng Zhang, Qiang Fei, Juan Li, Chuan Zhang, Ye Sun, Chunyan Zhu, Fengzhen Wang, Yueming Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4777557?pdf=render