Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits

Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits

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An off-the-shelf Raman Spectrometer (RS) was used to noninvasively determine the presence of monosodium urate (MSU) crystals on the metatarsophalangeal joint (MTPJ) of a single gout sufferer. The spectrum sourced from the clinically diagnosed gout sufferer was compared to that sourced from an age-ma...

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Main Authors: Declan J. Curran, Laurence Rubin, Mark R. Towler
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Online Access:https://doi.org/10.4137/CMAMD.S29061
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spelling doaj-634cfbc286714d67a544719482ad252b2020-11-25T03:07:31ZengSAGE PublishingClinical Medicine Insights: Arthritis and Musculoskeletal Disorders1179-54412015-01-01810.4137/CMAMD.S29061Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal DepositsDeclan J. Curran0Laurence Rubin1Mark R. Towler2Department of Mechanical and Industrial Engineering, Ryerson University, Toronto, ON, Canada.Division of Rheumatology, St. Michael's Hospital, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.Department of Biomedical Engineering, University Malaya, Kuala Lumpur, Malaysia.An off-the-shelf Raman Spectrometer (RS) was used to noninvasively determine the presence of monosodium urate (MSU) crystals on the metatarsophalangeal joint (MTPJ) of a single gout sufferer. The spectrum sourced from the clinically diagnosed gout sufferer was compared to that sourced from an age-matched healthy subject scanned using the same protocol. Minimal signal processing was conducted on both spectra. Peaks characteristic of MSU crystals were evident on the spectrum sourced from the gout sufferer and not on the spectrum from the healthy control.https://doi.org/10.4137/CMAMD.S29061
collection DOAJ
language English
format Article
sources DOAJ
author Declan J. Curran
Laurence Rubin
Mark R. Towler
spellingShingle Declan J. Curran
Laurence Rubin
Mark R. Towler
Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
author_facet Declan J. Curran
Laurence Rubin
Mark R. Towler
author_sort Declan J. Curran
title Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
title_short Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
title_full Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
title_fullStr Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
title_full_unstemmed Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
title_sort raman spectroscopy applied to the noninvasive detection of monosodium urate crystal deposits
publisher SAGE Publishing
series Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
issn 1179-5441
publishDate 2015-01-01
description An off-the-shelf Raman Spectrometer (RS) was used to noninvasively determine the presence of monosodium urate (MSU) crystals on the metatarsophalangeal joint (MTPJ) of a single gout sufferer. The spectrum sourced from the clinically diagnosed gout sufferer was compared to that sourced from an age-matched healthy subject scanned using the same protocol. Minimal signal processing was conducted on both spectra. Peaks characteristic of MSU crystals were evident on the spectrum sourced from the gout sufferer and not on the spectrum from the healthy control.
url https://doi.org/10.4137/CMAMD.S29061
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AT laurencerubin ramanspectroscopyappliedtothenoninvasivedetectionofmonosodiumuratecrystaldeposits
AT markrtowler ramanspectroscopyappliedtothenoninvasivedetectionofmonosodiumuratecrystaldeposits
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