Recent developments in the chemistry and biology of epothilones

Recent developments in the chemistry and biology of epothilones

Bibliographic Details
Main Authors:	Karl-Heinz Altmann, Frederic Cachoux, Giorgio Caravatti, Thomas Isarno, Markus Wartmann
Format:	Article
Language:	English
Published:	Arkat USA, Inc. 2006-09-01
Series:	ARKIVOC
Online Access:	https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0007.813

Similar Items

Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate
by: Fabienne Zdenka Gaugaz, et al.
Published: (2019-03-01)

Synthesis of epothilones and epothilone analogues
by: Sundermann, Kurt F.
Published: (2012)

Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)
by: Andrea Jantsch, et al.
Published: (2016-08-01)

Synthesis and Biological Evaluation of Open-Chain Epothilones
by: Fedorka, Sara R.
Published: (2012)

The chemistry and biology of mycolactones
by: Matthias Gehringer, et al.
Published: (2017-08-01)

Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues
by: Laura M. Woods, et al.
Published: (2017-03-01)

Novel microtubule-targeting agents &ndash; the epothilones
by: Daniel R Budman, et al.
Published: (2008-10-01)

Phylogeny‐guided characterization of glycosyltransferases for epothilone glycosylation
by: Peng Zhang, et al.
Published: (2019-07-01)

The Application of REDOR NMR to Understand the Conformation of Epothilone B
by: Jae-Ho Lee, et al.
Published: (2017-07-01)

NEW ADVANCES IN THE TREATMENT OF BREAST CANCER: THE ROLE EPOTHILONES
by: T. Y. SEMIGLAZOVA, et al.
Published: (2017-06-01)

TUBB3 role in the response of tumor cells to epothilones and taxanes
by: Agnieszka Marczak, et al.
Published: (2015-01-01)

Management of advanced breast cancer with the epothilone B analog, ixabepilone
by: William Gradishar
Published: (2009-06-01)

Experimental epothilone B neurotoxicity: Results of in vitro and in vivo studies
by: Alessia Chiorazzi, et al.
Published: (2009-08-01)

The Conformations of Cycloalkanes and The Conformations and Biochemical Activities of Both Epothilones and Macrolides
by: Guan-Hong Lai, et al.
Published: (2003)

Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons
by: Eun-Hae Jang, et al.
Published: (2016-01-01)

Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity
by: Huimin Wang, et al.
Published: (2021-04-01)

Recent developments of synthesis and biological activity of sultone scaffolds in medicinal chemistry
by: Yingying Xu, et al.
Published: (2021-04-01)

Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells
by: Jianhua Zhou, et al.
Published: (2020-05-01)

A bacterial negative transcription regulator binding on an inverted repeat in the promoter for epothilone biosynthesis
by: Xin-jing Yue, et al.
Published: (2017-05-01)

Epothilones in epithelial ovarian, fallopian tube, or primary peritoneal cancer: a systematic review
by: Zagouri F, et al.
Published: (2015-08-01)

Efficacy of epothilones in central nervous system trauma treatment: what has age got to do with it?
by: Jayden Clark, et al.
Published: (2021-01-01)

Mechanisms responsible for the inhibitory effects of epothilone B on scar formation after spinal cord injury
by: Wei Zhao, et al.
Published: (2017-01-01)

Epothilone D alters normal growth, viability and microtubule dependent intracellular functions of cortical neurons in vitro
by: J. A. Clark, et al.
Published: (2020-01-01)

Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea
by: Junheng Liang, et al.
Published: (2020-09-01)

A model study of epothilone synthesis: An alternative synthetic approach to the C1-C7 fragment
by: Lalić Gojko, et al.
Published: (2002-01-01)

A model study of epothilone synthesis: an alternative synthetic approach to the C1C7 fragment
by: RADOMIR N. SAICIC, et al.
Published: (2002-04-01)

A phase II trial of the epothilone B analog ixabepilone (BMS-247550) in patients with metastatic melanoma.
by: Patrick A Ott, et al.
Published: (2010-01-01)

Upregulation of Apol8 by Epothilone D facilitates the neuronal relay of transplanted NSCs in spinal cord injury
by: Weiwei Xue, et al.
Published: (2021-05-01)

The application of immobilized reagents and scavengers to multi-step organic synthesis : a total synthesis of epothilone C
by: Storer, Robert Ian
Published: (2003)

Chemistry of Bridged Lactams: Recent Developments
by: Roman Szostak, et al.
Published: (2019-01-01)

CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cluster for the epothilone production in Myxococcus xanthus
by: Ran Peng, et al.
Published: (2018-01-01)

Recent advances in ketene chemistry
by: Annette D. Allen, et al.
Published: (2016-11-01)

Development of Tools for Understanding Biological Sulfur Chemistry
by: Bailey, Thomas
Published: (2016)

Recent advances in the study of (–)clausenamide: chemistry, biological activities and mechanism of action
by: Shi-feng Chu, et al.
Published: (2014-12-01)

Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells
by: Chiara Trigili, et al.
Published: (2016-12-01)

An Easy and Efficient Strategy for the Enhancement of Epothilone Production Mediated by TALE-TF and CRISPR/dcas9 Systems in Sorangium cellulosum
by: Wei Ye, et al.
Published: (2019-11-01)

Recent Developments in Understanding Biochar’s Physical–Chemistry
by: Pellegrino Conte, et al.
Published: (2021-03-01)

Epothilone B Benefits Nigral Dopaminergic Neurons by Attenuating Microglia Activation in the 6-Hydroxydopamine Lesion Mouse Model of Parkinson’s Disease
by: Zhongyuan Yu, et al.
Published: (2018-09-01)

The Microtubule-Modulating Drug Epothilone D Alters Dendritic Spine Morphology in a Mouse Model of Mild Traumatic Brain Injury
by: Jyoti A. Chuckowree, et al.
Published: (2018-07-01)

Studies of nucleophile ring opening of oxabicyclic systems in highly polar media: application to a total synthesis of antitumor agent, (-)-epothilone
by: Diep, Nhut Kiet
Published: (2006)