Protective Effects of Liposomal Curcumin on Oxidative Stress/Antioxidant Imbalance, Metalloproteinases 2 and -9,Histological Changes and Renal Function in ExperimentalNephrotoxicity Induced by Gentamicin

Protective Effects of Liposomal Curcumin on Oxidative Stress/Antioxidant Imbalance, Metalloproteinases 2 and -9,Histological Changes and Renal Function in ExperimentalNephrotoxicity Induced by Gentamicin

Background: Our study aimed to assess the efficiency of Curcumin nanoformulation (LCC) on experimental nephrotoxicity induced by Gentamicin in rats. Methods: Six groups of seven rats were used: C—(control group) received saline solution i.p. (i.p. = intraperitoneal), G—gentamicin (G, 80 mg/kg body w...

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Bibliographic Details
Main Authors: Adriana Elena Bulboacă, Alina Porfire, Sorana D. Bolboacă, Cristina Ariadna Nicula, Dana Gabriela Feștilă, Alexandra Roman, Ruxandra Mioara Râjnoveanu, Armand Râjnoveanu, Gabriela Dogaru, Paul-Mihai Boarescu, Vasile Rus, Corneliu Angelo Bulboacă, Alexandra Ina Bulboacă, Ioana Stănescu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Antioxidants
Subjects:
Gentamicin induced nephrotoxicity
curcumin
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/10/2/325

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