Role of dopamine D2 receptors in optimizing choice strategy in a dynamic and uncertain environment

Role of dopamine D2 receptors in optimizing choice strategy in a dynamic and uncertain environment

In order to investigate roles of dopamine receptor subtypes in reward-based learning, we examined choice behavior of dopamine D1 and D2 receptor-knockout (D1R-KO and D2R-KO, respectively) mice in an instrumental learning task with progressively increasing reversal frequency and a dynamic two-armed b...

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Bibliographic Details
Main Authors: Shinae eKwak, Namjung eHuh, Ji-Seon eSeo, Jung-Eun eLee, Pyung-Lim eHan, Min W Jung
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Mouse
reinforcement learning
D1 receptor
dynamic foraging task
D2 receptor
reversal
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00368/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00368/full

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