Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.

Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.

Nucleoside analogues have attracted much attention due to their potential biological activities. Amongst all synthetic nucleosides, C5-modified pyrimidines and C7- or C8-modified purines have mostly been prepared using palladium cross-coupling reactions and then studied as antitumoral and antiviral...

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Bibliographic Details
Main Authors: CHRISTOPHE eLEN, Gwénaelle eHervé
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Chemistry
Subjects:
Water
green chemistry
Microwave
nucleotide
Nucleoside
Suzuki-Miyaura
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00010/full
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spelling doaj-63204540e5f242c69ef38e4db1fb08832020-11-24T21:05:15ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462015-02-01310.3389/fchem.2015.00010130213Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.CHRISTOPHE eLEN0Gwénaelle eHervé1Université de Technologie de CompiègneESCOMNucleoside analogues have attracted much attention due to their potential biological activities. Amongst all synthetic nucleosides, C5-modified pyrimidines and C7- or C8-modified purines have mostly been prepared using palladium cross-coupling reactions and then studied as antitumoral and antiviral agents. Our objective is to focus this review on the Suzuki-Miyaura and on the Heck cross-couplings of nucleosides using microwave irradiations which are an alternative technology compatible with green chemistry and sustainable development.http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00010/fullWatergreen chemistryMicrowavenucleotideNucleosideSuzuki-Miyaura
collection DOAJ
language English
format Article
sources DOAJ
author CHRISTOPHE eLEN
Gwénaelle eHervé
spellingShingle CHRISTOPHE eLEN
Gwénaelle eHervé
Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
Frontiers in Chemistry
Water
green chemistry
Microwave
nucleotide
Nucleoside
Suzuki-Miyaura
author_facet CHRISTOPHE eLEN
Gwénaelle eHervé
author_sort CHRISTOPHE eLEN
title Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
title_short Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
title_full Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
title_fullStr Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
title_full_unstemmed Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
title_sort aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
publisher Frontiers Media S.A.
series Frontiers in Chemistry
issn 2296-2646
publishDate 2015-02-01
description Nucleoside analogues have attracted much attention due to their potential biological activities. Amongst all synthetic nucleosides, C5-modified pyrimidines and C7- or C8-modified purines have mostly been prepared using palladium cross-coupling reactions and then studied as antitumoral and antiviral agents. Our objective is to focus this review on the Suzuki-Miyaura and on the Heck cross-couplings of nucleosides using microwave irradiations which are an alternative technology compatible with green chemistry and sustainable development.
topic Water
green chemistry
Microwave
nucleotide
Nucleoside
Suzuki-Miyaura
url http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00010/full
work_keys_str_mv AT christopheelen aqueousmicrowavesassistedcrosscouplingreactionsappliedtounprotectednucleosides
AT gwenaelleeherve aqueousmicrowavesassistedcrosscouplingreactionsappliedtounprotectednucleosides
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