Molecular characterization of two sub-family specific monoclonal antibodies to meningococcal Factor H binding protein

Molecular characterization of two sub-family specific monoclonal antibodies to meningococcal Factor H binding protein

Factor H binding protein (FHbp) is a component of two licensed vaccines for prevention of sepsis and meningitis caused by serogroup B meningococci. FHbp binds human Factor H (FH), which contributes to evasion of host immunity and FHbp sequence variants can be classified into two sub-families. Antibo...

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Bibliographic Details
Main Authors: C. Lo Passo, L. Zippilli, A. Angiolillo, I. Costa, I. Pernice, R. Galbo, F. Felici, P.T. Beernink
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Heliyon
Subjects:
Biochemistry
Immunology
Microbiology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017339282

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