Mature miR-99a Upregulation in the Amniotic Fluid Samples from Female Fetus Down Syndrome Pregnancies: A Pilot Study

Mature miR-99a Upregulation in the Amniotic Fluid Samples from Female Fetus Down Syndrome Pregnancies: A Pilot Study

<i>Background and Objective:</i> Although Down syndrome is the most frequent aneuploidy, its pathogenic molecular mechanisms are not yet fully understood. The aim of our study is to quantify&#8212;by qRT-PCR&#8212;the expression levels of both the mature forms and the pri-miRNAs...

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Main Authors: Anda-Cornelia Vizitiu, Danae Stambouli, Anca-Gabriela Pavel, Maria-Cezara Muresan, Diana Maria Anastasiu, Cristina Bejinar, Anda Alexa, Catalin Marian, Ioan Ovidiu Sirbu, Laurentiu Sima
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Medicina
Subjects:
down syndrome
amniotic fluid
pregnancy
microrna
cardiac defects
Online Access:https://www.mdpi.com/1010-660X/55/11/728

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