Intergenerational Transmission of Paternal Epigenetic Marks: Mechanisms Influencing Susceptibility to Post-Concussion Symptomology in a Rodent Model
Abstract Epigenetic transmission of phenotypic variance has been linked to paternal experiences prior to conception and during perinatal development. Previous reports indicate that paternal experiences increase phenotypic heterogeneity and may contribute to offspring susceptibility to post-concussiv...
Main Authors: | Harleen Hehar, Irene Ma, Richelle Mychasiuk |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-07784-7 |
Similar Items
-
The use of telomere length as a predictive biomarker for injury prognosis in juvenile rats following a concussion/mild traumatic brain injury
by: Harleen Hehar, et al.
Published: (2016-03-01) -
Diet, age, and prior injury status differentially alter behavioral outcomes following concussion in rats
by: Richelle Mychasiuk, et al.
Published: (2015-01-01) -
Impulsivity and Concussion in Juvenile Rats: Examining Molecular and Structural Aspects of the Frontostriatal Pathway.
by: Harleen Hehar, et al.
Published: (2015-01-01) -
Dietary intake alters behavioural recovery and gene expression profiles in the brain of juvenile rats that have experienced a concussion
by: Richelle eMychasiuk, et al.
Published: (2015-02-01) -
Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information
by: Upasna Sharma
Published: (2019-10-01)