Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10.

FilGAP is a Rac-specific GTPase-activating protein (GAP) that suppresses lamellae formation. In this study, we have identified RBM10 (RNA Binding Motif domain protein 10) as a FilGAP-interacting protein. Although RBM10 is mostly localized in the nuclei in human melanoma A7 cells, forced expression o...

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Bibliographic Details
Main Authors: Hazuki Yamada, Koji Tsutsumi, Yuki Nakazawa, Yoshio Shibagaki, Seisuke Hattori, Yasutaka Ohta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709192?pdf=render