ImmunoPET imaging of human CD8+ T cells with novel 68Ga-labeled nanobody companion diagnostic agents

ImmunoPET imaging of human CD8+ T cells with novel 68Ga-labeled nanobody companion diagnostic agents

Abstract Background Although immunotherapy has revolutionized treatment strategies for some types of cancers, most patients failed to respond or obtain long-term benefit. Tumor-infiltrating CD8+ T lymphocytes are closely related to the treatment outcome and prognosis of patients. Therefore, noninvas...

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Bibliographic Details
Main Authors: Haitao Zhao, Chao Wang, Yanling Yang, Yan Sun, Weijun Wei, Cheng Wang, Liangrong Wan, Cheng Zhu, Lianghua Li, Gang Huang, Jianjun Liu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Nanobiotechnology
Subjects:
CD8+ T lymphocytes
ImmunoPET
Nanobody
Immunotherapy
Companion diagnostics
Online Access:https://doi.org/10.1186/s12951-021-00785-9

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