Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
Hepatitis E virus (HEV) infection can result in severe placental disease, but mechanisms underlying pathogenicity are poorly understood. Here, the authors develop an ex vivo model for HEV infection at the maternal-fetal interface and compare pathogenicity of different HEV genotypes.
Main Authors: | Jordi Gouilly, Qian Chen, Johan Siewiera, Géraldine Cartron, Claude Levy, Martine Dubois, Reem Al-Daccak, Jacques Izopet, Nabila Jabrane-Ferrat, Hicham El Costa |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-07200-2 |
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