Differences in colonic crypt morphology of spontaneous and colitis-associated murine models via second harmonic generation imaging to quantify colon cancer development

Differences in colonic crypt morphology of spontaneous and colitis-associated murine models via second harmonic generation imaging to quantify colon cancer development

Abstract Background Colorectal cancer remains the second leading cause of cancer death in the United States, and increased risk in patients with ulcerative colitis (a subset of inflammatory bowel disease) has motivated studies into early markers of dysplasia. The development of clinically translatab...

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Bibliographic Details
Main Authors: Sandra P. Prieto, Cassandra L. Reed, Haley M. James, Kyle P. Quinn, Timothy J. Muldoon
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Inflammatory bowel disease
Multiphoton
Second harmonic generation
Image analysis
Crypt morphology
Online Access:http://link.springer.com/article/10.1186/s12885-019-5639-8

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http://link.springer.com/article/10.1186/s12885-019-5639-8

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