Neuronal control of peripheral insulin sensitivity and glucose metabolism

The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to dise...

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Main Authors:	Johan Ruud, Sophie M. Steculorum, Jens C. Brüning
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms15259

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spelling	doaj-62a98d37c005424dbfdf3e77a01d017e2021-05-11T07:17:14ZengNature Publishing GroupNature Communications2041-17232017-05-018111210.1038/ncomms15259Neuronal control of peripheral insulin sensitivity and glucose metabolismJohan Ruud0Sophie M. Steculorum1Jens C. Brüning2Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism ResearchDepartment of Neuronal Control of Metabolism, Max Planck Institute for Metabolism ResearchDepartment of Neuronal Control of Metabolism, Max Planck Institute for Metabolism ResearchThe brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease.https://doi.org/10.1038/ncomms15259
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Johan Ruud Sophie M. Steculorum Jens C. Brüning
spellingShingle	Johan Ruud Sophie M. Steculorum Jens C. Brüning Neuronal control of peripheral insulin sensitivity and glucose metabolism Nature Communications
author_facet	Johan Ruud Sophie M. Steculorum Jens C. Brüning
author_sort	Johan Ruud
title	Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_short	Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_full	Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_fullStr	Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_full_unstemmed	Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_sort	neuronal control of peripheral insulin sensitivity and glucose metabolism
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-05-01
description	The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease.
url	https://doi.org/10.1038/ncomms15259
work_keys_str_mv	AT johanruud neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism AT sophiemsteculorum neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism AT jenscbruning neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism
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Neuronal control of peripheral insulin sensitivity and glucose metabolism

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