Characterization of growth suppressive functions of a splice variant of cyclin D2.

Characterization of growth suppressive functions of a splice variant of cyclin D2.

We have recently cloned a novel splice variant of cyclin D2 termed as cycD2SV. CycD2SV overexpression in several immortalized cell lines led to formation of ubiquitinated protein aggregates accompanied by a significant decrease in cell proliferation. Based on immuno co-localization and ultrastructur...

Full description

Bibliographic Details
Main Authors: Karim Wafa, Jessica MacLean, Feixiong Zhang, Kishore B S Pasumarthi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542336?pdf=render

Similar Items

Similar Items