Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction.
In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug di...
Main Authors: | Yong Liu, Min Wu, Chunyan Miao, Peilin Zhao, Xiao-Li Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4752318?pdf=render |
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