miR-26a attenuates colitis and colitis-associated cancer by targeting the multiple intestinal inflammatory pathways

miR-26a attenuates colitis and colitis-associated cancer by targeting the multiple intestinal inflammatory pathways

Patients with inflammatory bowel disease are at increased risk for colitis-associated colorectal cancer (CAC). Therefore, controlling intestinal inflammation is a key therapeutic strategy for CAC. MicroRNAs (miRNAs or miRs) are a family of small noncoding RNAs that have the capacity to regulate fund...

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Bibliographic Details
Main Authors: Wei Zhang, Xianghui Fu, Jiansheng Xie, Hongming Pan, Weidong Han, Wendong Huang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MiR-26a
Intestinal inflammation
Colitis-associated carcinogenesis
NF-κB/STAT3
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000640

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