The Role of STAT3 in Non-Small Cell Lung Cancer
Persistent phosphorylation of signal transducer and activator of transcription 3 (STAT3) has been demonstrated in 22%~65% of non-small cell lung cancers (NSCLC). STAT3 activation is mediated by receptor tyrosine kinases, such as epidermal growth factor receptor (EGFR) and MET, cytokine receptors, s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-03-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/6/2/708 |