Prion protein polymorphisms affect chronic wasting disease progression.

Prion protein polymorphisms affect chronic wasting disease progression.

Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection. To test this effect, we orally inoculated 12 white-tailed deer with CWD agent. Three different PRNP alleles, wild-type (wt; glu...

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Bibliographic Details
Main Authors:	Chad J Johnson, Allen Herbst, Camilo Duque-Velasquez, Joshua P Vanderloo, Phil Bochsler, Rick Chappell, Debbie McKenzie
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3060816?pdf=render

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