Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV

Follicular helper T cells are critical in the generation of the antibody response. Here the authors show that adenosine deaminase is involved in the Tfh program and ensuring the provision of B cell help.

Bibliographic Details
Main Authors: Virginie Tardif, Roshell Muir, Rafael Cubas, Marita Chakhtoura, Peter Wilkinson, Talibah Metcalf, Rana Herro, Elias K. Haddad
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08801-1
Description
Summary:Follicular helper T cells are critical in the generation of the antibody response. Here the authors show that adenosine deaminase is involved in the Tfh program and ensuring the provision of B cell help.
ISSN:2041-1723