The FZD7‐TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma

The FZD7‐TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma

Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD7 has emerged as a potential therapeutic target because it is capable of transducing both canonical and noncanonical Wnt signals. In this study, we inves...

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Bibliographic Details
Main Authors: Ming Tan, Mohammad Asad, Valerie Heong, Meng Kang Wong, Tuan Zea Tan, Jieru Ye, Kuee Theng Kuay, Jean Paul Thiery, Clare Scott, Ruby Yun‐Ju Huang
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Molecular Oncology
Subjects:
anoikis
BCL2
FZD7
ovarian carcinoma
tumorigenesis
TWIST1
Online Access:https://doi.org/10.1002/1878-0261.12425

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