Majority rules with random tie-breaking in Boolean gene regulatory networks.

We consider threshold boolean gene regulatory networks, where the update function of each gene is described as a majority rule evaluated among the regulators of that gene: it is turned ON when the sum of its regulator contributions is positive (activators contribute positively whereas repressors con...

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Bibliographic Details
Main Authors: Claudine Chaouiya, Ouerdia Ourrad, Ricardo Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23922761/pdf/?tool=EBI