Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer.

Transcriptome sequencing of tumor subpopulations reveals a spectrum of therapeutic options for squamous cell lung cancer.

The only therapeutic options that exist for squamous cell lung carcinoma (SCC) are standard radiation and cytotoxic chemotherapy. Cancer stem cells (CSCs) are hypothesized to account for therapeutic resistance, suggesting that CSCs must be specifically targeted. Here, we analyze the transcriptome of...

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Bibliographic Details
Main Authors: Christian L Barrett, Richard B Schwab, HyunChul Jung, Brian Crain, Daniel J Goff, Catriona H M Jamieson, Patricia A Thistlethwaite, Olivier Harismendy, Dennis A Carson, Kelly A Frazer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3604164?pdf=render

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