Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene

Embryonic stem cells and induced pluripotent stem cells have the ability to maintain their telomere length via expression of an enzymatic complex called telomerase. Similarly, more than 85%–90% of cancer cells are found to upregulate the expression of telomerase, conferring them with the potential t...

Full description

Bibliographic Details
Main Authors: Muhammad Khairul Ramlee, Jing Wang, Wei Xun Toh, Shang Li
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Genes
Subjects:
telomerase
telomere
transcription regulation
promoter
mutation
Online Access:http://www.mdpi.com/2073-4425/7/8/50

Similar Items

Similar Items