VLSI Structures for DNA Sequencing—A Survey
DNA sequencing is a critical functionality in biomedical research, and technical advances that improve it have important implications for human health. Novel methods by which sequencing can be accomplished in more accurate, high-throughput, and faster ways are in development. Here, we review VLSI bi...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-05-01
|
| Series: | Bioengineering |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-5354/7/2/49 |
| id |
doaj-6256e5e85d1345ffbcbaee7f61fd9a84 |
|---|---|
| record_format |
Article |
| spelling |
doaj-6256e5e85d1345ffbcbaee7f61fd9a842020-11-25T03:12:25ZengMDPI AGBioengineering2306-53542020-05-017494910.3390/bioengineering7020049VLSI Structures for DNA Sequencing—A SurveyMohammad A. Islam0Palash K. Datta1Harley Myler2Phillip M. Drayer Department of Electrical Engineering, Lamar University, Beaumont, TX 77705, USAPhillip M. Drayer Department of Electrical Engineering, Lamar University, Beaumont, TX 77705, USAPhillip M. Drayer Department of Electrical Engineering, Lamar University, Beaumont, TX 77705, USADNA sequencing is a critical functionality in biomedical research, and technical advances that improve it have important implications for human health. Novel methods by which sequencing can be accomplished in more accurate, high-throughput, and faster ways are in development. Here, we review VLSI biosensors for nucleotide detection and DNA sequencing. Implementation strategies are discussed and split into function-specific architectures that are presented for reported design examples from the literature. Lastly, we briefly introduce a new approach to sequencing using Gate All-Around (GAA) nanowire Metal Oxide Semiconductor Field Effect Transistors (MOSFETs) that has significant implications for the field.https://www.mdpi.com/2306-5354/7/2/49DNA sequencingDNA hybridizationDNA sensorGAA nanowire MOSFET |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Mohammad A. Islam Palash K. Datta Harley Myler |
| spellingShingle |
Mohammad A. Islam Palash K. Datta Harley Myler VLSI Structures for DNA Sequencing—A Survey Bioengineering DNA sequencing DNA hybridization DNA sensor GAA nanowire MOSFET |
| author_facet |
Mohammad A. Islam Palash K. Datta Harley Myler |
| author_sort |
Mohammad A. Islam |
| title |
VLSI Structures for DNA Sequencing—A Survey |
| title_short |
VLSI Structures for DNA Sequencing—A Survey |
| title_full |
VLSI Structures for DNA Sequencing—A Survey |
| title_fullStr |
VLSI Structures for DNA Sequencing—A Survey |
| title_full_unstemmed |
VLSI Structures for DNA Sequencing—A Survey |
| title_sort |
vlsi structures for dna sequencing—a survey |
| publisher |
MDPI AG |
| series |
Bioengineering |
| issn |
2306-5354 |
| publishDate |
2020-05-01 |
| description |
DNA sequencing is a critical functionality in biomedical research, and technical advances that improve it have important implications for human health. Novel methods by which sequencing can be accomplished in more accurate, high-throughput, and faster ways are in development. Here, we review VLSI biosensors for nucleotide detection and DNA sequencing. Implementation strategies are discussed and split into function-specific architectures that are presented for reported design examples from the literature. Lastly, we briefly introduce a new approach to sequencing using Gate All-Around (GAA) nanowire Metal Oxide Semiconductor Field Effect Transistors (MOSFETs) that has significant implications for the field. |
| topic |
DNA sequencing DNA hybridization DNA sensor GAA nanowire MOSFET |
| url |
https://www.mdpi.com/2306-5354/7/2/49 |
| work_keys_str_mv |
AT mohammadaislam vlsistructuresfordnasequencingasurvey AT palashkdatta vlsistructuresfordnasequencingasurvey AT harleymyler vlsistructuresfordnasequencingasurvey |
| _version_ |
1724650456115838976 |