Kinetic Modeling of the Genetic Information Processes in a Minimal Cell

Kinetic Modeling of the Genetic Information Processes in a Minimal Cell

JCVI-syn3A is a minimal bacterial cell with a 543 kbp genome consisting of 493 genes. For this slow growing minimal cell with a 105 min doubling time, we recently established the essential metabolism including the transport of required nutrients from the environment, the gene map, and genome-wide pr...

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Bibliographic Details
Main Authors: Zane R. Thornburg, Marcelo C. R. Melo, David Bianchi, Troy A. Brier, Cole Crotty, Marian Breuer, Hamilton O. Smith, Clyde A. Hutchison, John I. Glass, Zaida Luthey-Schulten
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
minimal cells
stochastic simulations
kinetic parameters
DNA replication
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Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00130/full

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https://www.frontiersin.org/article/10.3389/fmolb.2019.00130/full

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