Exploiting Cell Death Pathways for Inducible Cell Elimination to Modulate Graft-versus-Host-Disease

Exploiting Cell Death Pathways for Inducible Cell Elimination to Modulate Graft-versus-Host-Disease

Hematopoietic stem cell transplantation is a potent form of immunotherapy, potentially life-saving for many malignant hematologic diseases. However, donor lymphocytes infused with the graft while exerting a graft versus malignancy effect can also cause potentially fatal graft versus host disease (GV...

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Bibliographic Details
Main Authors: Corey Falcon, Mustafa AL-Obaidi, Antonio Di Stasi
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Biomedicines
Subjects:
cellular therapies
graft versus host disease (GVHD)
inducible suicide genes
apoptosis
necroptosis
Online Access:http://www.mdpi.com/2227-9059/5/2/30

Internet

http://www.mdpi.com/2227-9059/5/2/30

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