Downregulation of miR-654-3p in Colorectal Cancer Indicates Poor Prognosis and Promotes Cell Proliferation and Invasion by Targeting SRC

Downregulation of miR-654-3p in Colorectal Cancer Indicates Poor Prognosis and Promotes Cell Proliferation and Invasion by Targeting SRC

BackgroundMicroRNAs (miRNAs), such as miR-654-3p, regulate gene expression at the post-transcriptional level affecting malignant tumor behavior. However, the expression levels, function, and mechanism of miR-654-3p in colorectal cancer (CRC) are unknown.MethodsThe expression levels of miR-654-3p and...

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Bibliographic Details
Main Authors: Haoran Zhang, Zhanlong Shen, Yushi Zhou, Zhen Zhang, Quan Wang, Mengmeng Zhang, Kewei Jiang, Shan Wang, Yingjiang Ye, Bo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
colorectal cancer
miR-654-3p
SRC
proliferation
invasion
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.577948/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.577948/full

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