Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma

Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma

Human eosinophils release numerous cytokines that are pre-synthesized and stored within their cytoplasmic-specific (secretory) granules. For example, high levels of interferon-gamma (IFN-γ) are constitutively expressed in these cells, but the intracellular compartments involved in the transport and...

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Bibliographic Details
Main Authors: Lívia A. S. Carmo, Kennedy Bonjour, Lisa A. Spencer, Peter F. Weller, Rossana C. N. Melo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
cytokines
cell activation
degranulation
inflammation
immunonanogold electron microscopy
eosinophil
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01542/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01542/full

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