A general dose-response relationship for chronic chemical and other health stressors and mixtures based on an emergent illness severity model.
Current efforts to assess human health response to chemicals based on high-throughput in vitro assay data on intra-cellular changes have been hindered for some illnesses by lack of information on higher-level extracellular, inter-organ, and organism-level interactions. However, a dose-response funct...
Main Authors: | James D Englehardt, Weihsueh A Chiu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0211780 |
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