Brain activation and subjective anxiety during an anticipatory anxiety task is related to clinical outcome during prazosin treatment for alcohol use disorder

Brain activation and subjective anxiety during an anticipatory anxiety task is related to clinical outcome during prazosin treatment for alcohol use disorder

Background: Higher levels of anxiety, negative affect, and impaired emotion regulation are associated with alcohol use disorder (AUD) and contribute to relapse and worse treatment outcomes. Prazosin, while typically used to treat post-traumatic stress disorder (PTSD) and other anxiety disorders, has...

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Bibliographic Details
Main Authors: Claire E. Wilcox, Bryon Adinoff, Joshua Clifford, Josef Ling, Katie Witkiewitz, Andrew R. Mayer, Kylar M. Boggs, Matthew Eck, Michael Bogenschutz
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Prazosin
Anticipatory anxiety task
Alcohol use disorder
fMRI
Stress
Treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220300012

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