Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction.

Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction.

Irisin, a newly discovered myokine, is considered as a promising candidate for the treatment of metabolic disturbances and cardiovascular diseases. In the present study, we used two animal models, apolipoprotein E-deficient mice fed on a high-cholesterol diet and a mouse carotid partial ligation mod...

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Bibliographic Details
Main Authors: Yuzhu Zhang, Qian Mu, Zheng Zhou, Haibo Song, Yuan Zhang, Fei Wu, Miao Jiang, Fang Wang, Wen Zhang, Liang Li, Lei Shao, Xingli Wang, Shiwu Li, Lijun Yang, Qi Wu, Mingxiang Zhang, Dongqi Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4927070?pdf=render

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