A vaccine targeted at CETP alleviates high fat and high cholesterol diet-induced atherosclerosis and non-alcoholic steatohepatitis in rabbit.

A vaccine targeted at CETP alleviates high fat and high cholesterol diet-induced atherosclerosis and non-alcoholic steatohepatitis in rabbit.

Low HDL-C levels are associated with atherosclerosis and non-alcoholic steatohepatitis, and increased levels may reduce the risk of these diseases. Inhibition of cholesteryl ester transfer protein (CETP) activity is considered a promising strategy for increasing HDL-C levels. Since CETP is a self-an...

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Bibliographic Details
Main Authors: Yi-Wei Liaw, Chi-Yu Lin, Yu-Sheng Lai, Tzu-Chung Yang, Chau-Jong Wang, Jacqueline Whang-Peng, Leroy F Liu, Chia-Po Lin, Shin Nieh, Shao-Chun Lu, Jaulang Hwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259298?pdf=render

Internet

http://europepmc.org/articles/PMC4259298?pdf=render

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