Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level.

Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level.

To activate clot formation and maintain hemostasis, platelets adhere and spread onto sites of vascular injury. Although this process is well-characterized biochemically, how the physical and spatial cues in the microenvironment affect platelet adhesion and spreading remain unclear. In this study, we...

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Bibliographic Details
Main Authors: Ashley Kita, Yumiko Sakurai, David R Myers, Ross Rounsevell, James N Huang, Tae Joon Seok, Kyoungsik Yu, Ming C Wu, Daniel A Fletcher, Wilbur A Lam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197646?pdf=render

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http://europepmc.org/articles/PMC3197646?pdf=render

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