1α, 25-dihydroxy Vitamin D3 containing fractions of Catharanthus roseus leaf aqueous extract inhibit preadipocyte differentiation and induce lipolysis in 3T3-L1 cells

1α, 25-dihydroxy Vitamin D3 containing fractions of Catharanthus roseus leaf aqueous extract inhibit preadipocyte differentiation and induce lipolysis in 3T3-L1 cells

Abstract Background To investigate the potential of Catharanthus roseus leaf aqueous crude extract (CRACE) as a regulator of adipocyte development and function. Methods 3T3-L1 adipogenesis model was used to investigate the effect of CRACE on adipogenesis. 3T3-L1 preadipocytes (for adipogenic differe...

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Bibliographic Details
Main Authors: Anuj Kumar Borah, Archana Singh, Rafika Yasmin, Robin Doley, Venkata Satish Kumar Mattaparthi, Sougata Saha
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Catharanthus roseus
Obesity
Lipolysis
Adipogenesis
3T3-L1
Vitamin D3
Online Access:https://doi.org/10.1186/s12906-019-2754-7

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