<i>Mycobacterium tuberculosis</i> Rv2005c Induces Dendritic Cell Maturation and Th1 Responses and Exhibits Immunotherapeutic Activity by Fusion with the Rv2882c Protein

<i>Mycobacterium tuberculosis</i> Rv2005c Induces Dendritic Cell Maturation and Th1 Responses and Exhibits Immunotherapeutic Activity by Fusion with the Rv2882c Protein

Immunotherapy represents a promising approach for improving current antibiotic treatments through the engagement of the host’s immune system. Latency-associated antigens have been included as components of multistage subunit tuberculosis vaccines. We first identified Rv2005c, a DosR regulon-encoded...

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Bibliographic Details
Main Authors: Yong Woo Back, Ki Won Shin, Seunga Choi, Hye-Soo Park, Kang-In Lee, Han-Gyu Choi, Hwa-Jung Kim
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
<i>Mycobacterium tuberculosis</i>
hypoxia
DosR
chemo-immunotherapy
multifunctional T cell
Online Access:https://www.mdpi.com/2076-393X/8/3/370

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