Neuroinflammation and neurodegeneration in adult rat brain from binge ethanol exposure: abrogation by docosahexaenoic acid.

Evidence that brain edema and aquaporin-4 (AQP4) water channels have roles in experimental binge ethanol-induced neurodegeneration has stimulated interest in swelling/edema-linked neuroinflammatory pathways leading to oxidative stress. We report here that neurotoxic binge ethanol exposure produces c...

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Bibliographic Details
Main Authors: Nuzhath Tajuddin, Kwan-Hoon Moon, S Alex Marshall, Kimberly Nixon, Edward J Neafsey, Hee-Yong Kim, Michael A Collins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4100731?pdf=render