Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease

Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease

Parkinson's disease (PD) is the most common form of neurodegenerative movement disorder, associated with profound loss of dopaminergic neurons from the basal ganglia. Though loss of dopaminergic neuron cell bodies from the substantia nigra pars compacta is a well-studied feature, atrophy and lo...

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Bibliographic Details
Main Authors: Owen M. Peters, Alexandra Weiss, Jake Metterville, Lina Song, Robert Logan, Gaynor A. Smith, Michael A. Schwarzschild, Christian Mueller, Robert H. Brown, Marc Freeman
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neurobiology of Disease
Subjects:
Axon destruction
Parkinson's disease
Sarm1
Alpha-synuclein
Axotomy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121001170

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