A novel experimental porcine model to assess the impact of differential pulmonary blood flow on ischemia–reperfusion injury after unilateral lung transplantation

A novel experimental porcine model to assess the impact of differential pulmonary blood flow on ischemia–reperfusion injury after unilateral lung transplantation

Abstract Background Primary graft dysfunction (PGD) remains a major obstacle after lung transplantation. Ischemia–reperfusion injury is a known contributor to the development of PGD following lung transplantation. We developed a novel approach to assess the impact of increased pulmonary blood flow i...

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Bibliographic Details
Main Authors: Anna Elisabeth Frick, Michaela Orlitová, Arno Vanstapel, Sofie Ordies, Sandra Claes, Dominique Schols, Tobias Heigl, Janne Kaes, Berta Saez-Gimenez, Robin Vos, Geert M. Verleden, Bart Vanaudenaerde, Stijn E. Verleden, Dirk E. Van Raemdonck, Arne P. Neyrinck
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Intensive Care Medicine Experimental
Subjects:
Porcine left lung transplantation
Primary graft dysfunction
Pulmonary vascular resistance
Online Access:https://doi.org/10.1186/s40635-021-00371-1

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