Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase.

Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase.

Antimicrobial resistance is a growing global health and economic concern. Current antimicrobial agents are becoming less effective against common bacterial infections. We previously identified pyrrolocins A and C, which showed activity against a variety of Gram-positive bacteria. Structurally simila...

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Bibliographic Details
Main Authors: Erica C Larson, Albebson L Lim, Christopher D Pond, Matthew Craft, Mirela Čavužić, Grover L Waldrop, Eric W Schmidt, Louis R Barrows
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233485

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https://doi.org/10.1371/journal.pone.0233485

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