A trial like ALIC4E: why design a platform, response-adaptive, open, randomised controlled trial of antivirals for influenza-like illness?

ALIC4E is the first publicly funded, multicountry, pragmatic study determining whether antivirals should be routinely prescribed for influenza-like illness in primary care. The trial aims to go beyond determining the average treatment effect in a population to determining effects in patients with co...

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Bibliographic Details
Main Authors: Christopher C. Butler, Samuel Coenen, Benjamin R. Saville, Johanna Cook, Alike van der Velden, Jane Homes, Menno de Jong, Paul Little, Herman Goossens, Philippe Beutels, Margareta Ieven, Nick Francis, Pieter Moons, Emily Bongard, Theo Verheij
Format: Article
Language:English
Published: European Respiratory Society 2018-05-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/4/2/00046-2018.full