Accurate diagnosis of prostate cancer using logistic regression

A new logistic regression-based method to distinguish between cancerous and noncancerous RNA genomic data is developed and tested with 100% precision on 595 healthy and cancerous prostate samples. A logistic regression system is developed and trained using whole-exome sequencing data at a high-level...

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Bibliographic Details
Main Author: Hooshmand Arash
Format: Article
Language:English
Published: De Gruyter 2021-03-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2021-0238
Description
Summary:A new logistic regression-based method to distinguish between cancerous and noncancerous RNA genomic data is developed and tested with 100% precision on 595 healthy and cancerous prostate samples. A logistic regression system is developed and trained using whole-exome sequencing data at a high-level, i.e., normalized quantification of RNAs obtained from 495 prostate cancer samples from The Cancer Genome Atlas and 100 healthy samples from the Genotype-Tissue Expression project. We could show that both sensitivity and specificity of the method in the classification of cancerous and noncancerous cells are perfectly 100%.
ISSN:2391-5463