The contribution of the maternal immune system to the establishment of pregnancy in cattle

Immune cells play an integral role in effecting successful reproductive function. Indeed disturbed or aberrant immune function has been identified as primary mechanisms behind infertility. In contrast to the extensive body of literature that exists for human and mouse, studies detailing the immunolo...

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Main Author:	Trudee eFair
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-01-01
Series:	Frontiers in Immunology
Subjects:	Fertility macrophage cytokine Immune function Cow
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00007/full

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spelling	doaj-616fd41bde534c2789580489517f78732020-11-25T01:28:26ZengFrontiers Media S.A.Frontiers in Immunology1664-32242015-01-01610.3389/fimmu.2015.00007122902The contribution of the maternal immune system to the establishment of pregnancy in cattleTrudee eFair0University College DublinImmune cells play an integral role in effecting successful reproductive function. Indeed disturbed or aberrant immune function has been identified as primary mechanisms behind infertility. In contrast to the extensive body of literature that exists for human and mouse, studies detailing the immunological interaction between the embryo and the maternal endometrium are quite few in cattle. Nevertheless, by reviewing the existing studies and extrapolating from sheep, pig, mouse and human data we can draw a reasonably comprehensive picture of immune cell involvement from follicle development, ovulation, gamete transfer, maternal recognition of pregnancy, implantation and placentation. These events are reviewed in detailed below and key findings are discussed.http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00007/fullFertilitymacrophagecytokineImmune functionCow
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Trudee eFair
spellingShingle	Trudee eFair The contribution of the maternal immune system to the establishment of pregnancy in cattle Frontiers in Immunology Fertility macrophage cytokine Immune function Cow
author_facet	Trudee eFair
author_sort	Trudee eFair
title	The contribution of the maternal immune system to the establishment of pregnancy in cattle
title_short	The contribution of the maternal immune system to the establishment of pregnancy in cattle
title_full	The contribution of the maternal immune system to the establishment of pregnancy in cattle
title_fullStr	The contribution of the maternal immune system to the establishment of pregnancy in cattle
title_full_unstemmed	The contribution of the maternal immune system to the establishment of pregnancy in cattle
title_sort	contribution of the maternal immune system to the establishment of pregnancy in cattle
publisher	Frontiers Media S.A.
series	Frontiers in Immunology
issn	1664-3224
publishDate	2015-01-01
description	Immune cells play an integral role in effecting successful reproductive function. Indeed disturbed or aberrant immune function has been identified as primary mechanisms behind infertility. In contrast to the extensive body of literature that exists for human and mouse, studies detailing the immunological interaction between the embryo and the maternal endometrium are quite few in cattle. Nevertheless, by reviewing the existing studies and extrapolating from sheep, pig, mouse and human data we can draw a reasonably comprehensive picture of immune cell involvement from follicle development, ovulation, gamete transfer, maternal recognition of pregnancy, implantation and placentation. These events are reviewed in detailed below and key findings are discussed.
topic	Fertility macrophage cytokine Immune function Cow
url	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00007/full
work_keys_str_mv	AT trudeeefair thecontributionofthematernalimmunesystemtotheestablishmentofpregnancyincattle AT trudeeefair contributionofthematernalimmunesystemtotheestablishmentofpregnancyincattle
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The contribution of the maternal immune system to the establishment of pregnancy in cattle

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