Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice.

Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice.

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a severe and life-threatening acute lung injury (ALI) that is caused by noxious stimuli and pathogens. ALI is characterized by marked acute inflammation with elevated alveolar cytokine levels. Mitogen-activated protein kinase (MAPK) pathways...

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Bibliographic Details
Main Authors: Yang Xu, Toshihiro Ito, Soichiro Fushimi, Sakuma Takahashi, Junya Itakura, Ryojiro Kimura, Miwa Sato, Megumi Mino, Akihiko Yoshimura, Akihiro Matsukawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4183529?pdf=render

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http://europepmc.org/articles/PMC4183529?pdf=render

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