Purified Brominated Indole Derivatives from Dicathais orbita Induce Apoptosis and Cell Cycle Arrest in Colorectal Cancer Cell Lines

Purified Brominated Indole Derivatives from Dicathais orbita Induce Apoptosis and Cell Cycle Arrest in Colorectal Cancer Cell Lines

Dicathais orbita is a large Australian marine gastropod known to produce bioactive compounds with anticancer properties. In this research, we used bioassay guided fractionation from the egg mass extract of D. orbita using flash column chromatography and identified fractions containing tyrindoleninon...

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Bibliographic Details
Main Authors: Babak Esmaeelian, Kirsten Benkendorff, Catherine A. Abbott, Martin R. Johnston
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Marine Drugs
Subjects:
colorectal cancer
apoptosis
marine mollusc
brominated indoles
Online Access:http://www.mdpi.com/1660-3397/11/10/3802

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