IκB kinases increase Myc protein stability and enhance progression of breast cancer cells
<p>Abstract</p> <p>Background</p> <p>Both IκB kinase (IKK) complex and oncgenic protein Myc play important roles in cancer progression, including cancer cell invasiveness and metastasis. The levels of Myc is regulated by the phosphorylation of Myc at Thr58 and Ser62.<...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-05-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/10/1/53 |